Development of antiretroviral drug resistance.

  title={Development of antiretroviral drug resistance.},
  author={Mark A. Wainberg and Gerasimos J Zaharatos and Bluma G Brenner},
  journal={The New England journal of medicine},
  volume={365 7},
Copyright © 2011 Massachusetts Medical Society. Combinations of antiretroviral drugs are efficacious in the treatment of human immunodeficiency virus (HIV) infection, regardless of the viral subtype. However, the level of resistance to antiretroviral drugs differs among HIV variants. Indeed, we have limited knowledge of resistance mutations in non-B subtypes of HIV type 1 (HIV-1) and their clinical relevance, despite the fact that more than 90% of patients with HIV-1 infection worldwide have… CONTINUE READING
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