Development of an in vitro culture system for the study of osteoclast activity and function.

Abstract

Resorption is a difficult process to study in vivo because of the complex organization of mineralized tissue. The objective of this study was to develop an in vitro culture system for studying osteoclast attachment and activity. Transparent, microporous substrata were prepared using radio frequency-sputtering techniques to apply a thin layer of… (More)

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