Development of an improved animal model of experimental autoimmune myositis.

Abstract

Multiple animal models of experimental autoimmune myositis (EAM) have been developed. However, these models vary greatly in the severity of disease and reproducibility. The goal of this study was to test whether vaccination twice with increased dose of rat myosin and pertussis toxin (PT) could induce EAM with severer disease in mice. BALB/c mice were… (More)

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@article{Kang2015DevelopmentOA, title={Development of an improved animal model of experimental autoimmune myositis.}, author={Juan Kang and Hong-ya Zhang and Guo-dong Feng and Dong-Yun Feng and Hong-ge Jia}, journal={International journal of clinical and experimental pathology}, year={2015}, volume={8 11}, pages={14457-64} }