Development of an eight gene expression profile implicating human breast tumours of all grade

@article{Gabrovska2011DevelopmentOA,
  title={Development of an eight gene expression profile implicating human breast tumours of all grade},
  author={Plamena N. Gabrovska and Robert Anthony Smith and Thomas Tiang and Stephen R. Weinstein and Larisa M. Haupt and Lyn. R. Griffiths},
  journal={Molecular Biology Reports},
  year={2011},
  volume={39},
  pages={3879-3892}
}
The goal of improving systemic treatment of breast cancers is to evolve from treating every patient with non-specific cytotoxic chemotherapy/hormonal therapy, to a more individually-tailored direct treatment. Although anatomic staging and histological grade are important prognostic factors, they often fail to predict the clinical course of this disease. This study aimed to develop a gene expression profile associated with breast cancers of differing grades. We extracted mRNA from FFPE archival… CONTINUE READING
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