Development of an antimicrobial formulation for control of specimen-related contamination in phage-based diagnostic testing for tuberculosis.

@article{Albert2007DevelopmentOA,
  title={Development of an antimicrobial formulation for control of specimen-related contamination in phage-based diagnostic testing for tuberculosis.},
  author={Heidi Albert and Andr{\'e} Phillip Trollip and K Linley and Celeste Abrahams and Todd Seaman and Richard J Mole},
  journal={Journal of applied microbiology},
  year={2007},
  volume={103 4},
  pages={892-9}
}
AIMS To develop and evaluate an antimicrobial supplement for use with phage-based tests for rapid detection of drug resistance of tuberculosis (TB). METHODS AND RESULTS An antimicrobial formulation containing nystatin, oxacillin and aztreonam (NOA) (final concentrations of 50,000 IU l(-1), 2 mg l(-1), and 30 mg l(-1) respectively) was developed. This formulation was tested for its influence on detection of a number of Mycobacterium tuberculosis (MTB) strains using the phage amplification… CONTINUE READING