Development of an IgM-capture ELISA for Coxsackievirus A16 infection.

  title={Development of an IgM-capture ELISA for Coxsackievirus A16 infection.},
  author={Feihai Xu and Delei He and Shuizhen He and Bin Wu and Li Guan and Jianjun Niu and Liang Li and Chuan Li and Zuxing Weng and Qiang Yan and Lisheng Yang and Shengxiang Ge and Tong Cheng and Yixin Chen and Jun Yu Zhang and Ningshao Xia},
  journal={Journal of virological methods},
  volume={171 1},
Diagnosis of Coxsackievirus A16 (CA16) infection in China relies mainly on reverse transcription-polymerase chain reaction (RT-PCR) that require expensive equipment and special trained personnel, thus making its wide application in health care settings unlikely. In this study, a novel IgM anti-CA16 assay was developed for the detection of IgM antibodies to CA16 in serum. The responses and diagnostic value of IgM for the CA16 infection were assessed by testing 1970 serum samples. The results… CONTINUE READING

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