Development of an HPLC-PAD-MS assay for the identification and quantification of major phenolic edelweiss (Leontopodium alpium Cass.) constituents.

@article{Schwaiger2006DevelopmentOA,
  title={Development of an HPLC-PAD-MS assay for the identification and quantification of major phenolic edelweiss (Leontopodium alpium Cass.) constituents.},
  author={Stefan Schwaiger and Christoph Seger and Bettina Wiesbauer and Peter Josef Schneider and Ernst Peter Ellmerer and Sonja Sturm and Hermann Stuppner},
  journal={Phytochemical analysis : PCA},
  year={2006},
  volume={17 5},
  pages={291-8}
}
The analytical assessment of edelweiss (Leontopodium alpinum) herb extracts, used in traditional alpine medicine, has resulted in the development of a HPLC-PAD-MS method that allows baseline separation of almost all constituents. Peak assignment of 14 analytes was achieved by comparison of retention times, UV and mass spectra with those of reference compounds either commercially available (luteolin, apigenin and chlorogenic acid) or isolated from edelweiss plants by column chromatography. Ten… CONTINUE READING

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