Development of adjuvant-active nonionic block copolymers.

  title={Development of adjuvant-active nonionic block copolymers.},
  author={Todd and Balusubramanian and Newman},
  journal={Advanced drug delivery reviews},
  volume={32 3},
Nonionic block copolymers are surfactants synthesized using propylene oxide (PO) and ethylene oxide (EO) which are organized as 'blocks' of polyoxyethylene (POE) and polyoxypropylene (POP). These copolymers can be designed and synthesized using variable amounts of the PO and EO and with differential arrangement of the POP and POE blocks so that individual products have unique physicochemical properties. The copolymers that have been most thoroughly evaluated in vaccine research are linear with… CONTINUE READING


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