Development of acute lymphoblastic leukemia in a child after treatment of Langerhans cell histiocytosis: report of one case.

@article{Wu1999DevelopmentOA,
  title={Development of acute lymphoblastic leukemia in a child after treatment of Langerhans cell histiocytosis: report of one case.},
  author={J H Wu and Marvin Louis Roy Lu and K H Lin and S T Jou and David T. Lin},
  journal={Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi},
  year={1999},
  volume={40 6},
  pages={441-2}
}
Langerhans cell histiocytosis (LCH) is a group of poorly understood disorders. To our knowledge, LCH is a non-malignant disorder. The association of LCH with a secondary neoplasm has not been well assessed, however, a few cases have been reported. We report a case of LCH, a localized osteolytic lesion over metaphysis of left femur, who was treated with local curettage and chemotherapy with vincristine, prednisone and 6-mercaptopurine (6-MP) for eight months from end of 1991 to August, 1992. Six… CONTINUE READING