Development of a urodilatin-specific antibody and radioimmunoassay for urodilatin in human urine.

@article{Carstens1997DevelopmentOA,
  title={Development of a urodilatin-specific antibody and radioimmunoassay for urodilatin in human urine.},
  author={J. Carstens and K. Jensen and P. Ivarsen and L. Rasmussen and E. Pedersen},
  journal={Clinical chemistry},
  year={1997},
  volume={43 4},
  pages={
          638-43
        }
}
Urodilatin (URO) (95-126) is a renal-derived natriuretic peptide that is isolated only from human urine. This study describes the development of a URO-specific antibody and a RIA for URO in urine. At present, there is no commonly available URO-specific antibody. We produced a URO-specific antibody without cross-reactivity with atrial natriuretic peptide (ANP) analogs by immunization of rabbits with the URO (95-126) peptide and subsequent purification of the resulting URO antiserum with affinity… Expand
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