Development of a specially tailored local drug delivery system for the prevention of fibrosis after insertion of cochlear implants into the inner ear.

@article{Bohl2012DevelopmentOA,
  title={Development of a specially tailored local drug delivery system for the prevention of fibrosis after insertion of cochlear implants into the inner ear.},
  author={Anne Bohl and Henning W Rohm and Piera Ceschi and Gerrit Paasche and Anne Hahn and Stephan Barcikowski and Thomas Lenarz and Timo St{\"o}ver and Hans-Wilhelm Pau and Klaus-Peter Schmitz and K. Sternberg},
  journal={Journal of materials science. Materials in medicine},
  year={2012},
  volume={23 9},
  pages={2151-62}
}
A cochlear implant (CI)-associated local drug delivery system based on dexamethasone (DMS) was developed with the purpose to inhibit the growth of fibrotic tissue which influences the signal transmission from the CI to the neurons of the inner ear. For the realization of a targeted DMS delivery the following concepts were combined: modification of the… CONTINUE READING