Development of a single nucleotide polymorphism DNA microarray for the detection and genotyping of the SARS coronavirus.

  title={Development of a single nucleotide polymorphism DNA microarray for the detection and genotyping of the SARS coronavirus.},
  author={Xi Guo and Peng Geng and Quan Wang and Boyang Cao and Bin Liu},
  journal={Journal of microbiology and biotechnology},
  volume={24 10},
  • Xi GuoP. Geng B. Liu
  • Published 28 October 2014
  • Biology
  • Journal of microbiology and biotechnology
Severe acute respiratory syndrome (SARS), a disease that spread widely in the world during late 2002 to 2004, severely threatened public health. Although there have been no reported infections since 2004, the extremely pathogenic SARS coronavirus (SARS-CoV), as the causative agent of SARS, has recently been identified in animals, showing the potential for the re-emergence of this disease. Previous studies showed that 27 single nucleotide polymorphism (SNP) mutations among the spike (S) gene of… 

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