Development of a simple model for studying the effects of antifungal agents on multicellular communities of Aspergillus fumigatus.

  title={Development of a simple model for studying the effects of antifungal agents on multicellular communities of Aspergillus fumigatus.},
  author={Eilidh Mowat and J. Butcher and Sue Lang and Craig Williams and Gordon Ramage},
  journal={Journal of medical microbiology},
  volume={56 Pt 9},
Aspergillus fumigatus is an increasingly prevalent opportunistic fungal pathogen of various immunocompromised individuals. It has the ability to form filaments within the lungs, producing dense intertwined mycelial balls, which are difficult to treat. The aim of this study was to develop a suitable model of A. fumigatus to examine the effects of antifungal challenge on these intertwined filamentous communities. A. fumigatus NCPF 7367 growth conditions were optimized on both Thermanox coverslips… CONTINUE READING


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