Development of a sensitive deaminated single-strand conformation polymorphism (DSSCP).

Abstract

The single-strand conformation polymorphism (SSCP), accompanied by sequencing, is a useful methods for identifying mutations in a DNA fragment. In this study, we have developed a modified SSCP with the aid of sodium bisulfite treatment. The corresponding PCR products for exon 3 of Hb gene were sequenced and samples with homozygote and heterozygote single… (More)
DOI: 10.1007/s12010-009-8595-y

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