Development of a sensitive and selective method for the quantitative analysis of cortisol, cortisone, prednisolone and prednisone in human plasma.

Abstract

A highly selective, sensitive and robust LC-MS/MS method was developed for the simultaneous quantification of cortisol, cortisone, prednisolone and prednisone in human plasma. Prednisolone, cortisol and cortisone have similar fragmentation pattern. These three compounds were chromatographically separated, thus eliminating the inherent interference that… (More)
DOI: 10.1016/j.jchromb.2009.02.019

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Cite this paper

@article{Ionita2009DevelopmentOA, title={Development of a sensitive and selective method for the quantitative analysis of cortisol, cortisone, prednisolone and prednisone in human plasma.}, author={Ileana A Ionita and Douglas M. Fast and Fatemeh Akhlaghi}, journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences}, year={2009}, volume={877 8-9}, pages={765-72} }