Development of a rational scale to assess the harm of drugs of potential misuse

@article{Nutt2007DevelopmentOA,
  title={Development of a rational scale to assess the harm of drugs of potential misuse},
  author={David J. Nutt and Leslie A King and William Saulsbury and Colin Blakemore},
  journal={The Lancet},
  year={2007},
  volume={369},
  pages={1047-1053}
}

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References

SHOWING 1-10 OF 36 REFERENCES

Comparison of acute lethal toxicity of commonly abused psychoactive substances.

A structured English-language literature search was conducted to identify experimental studies and clinical reports that documented human and non-human lethal doses of 20 abused substances that are distributed widely in Europe and North America.

Toward a comparative overview of dependence potential and acute toxicity of psychoactive substances used nonmedically.

  • R. Gable
  • Psychology
    The American journal of drug and alcohol abuse
  • 1993
A procedure is outlined for comparing dependence potential and acute toxicity across a broad range of abused psychoactive substances and it is suggested that the margin of safety ("therapeutic index") varied dramatically between substances.

Comparative Epidemiology of Dependence on Tobacco , Alcohol , Controlled Substances , and Inhalants : Basic Findings From the National Comorbidity Survey

The development of the Smoking Cessation Quality of Life questionnaire is described, a self-reported measure designed to quantify the impact of smoking cessation on perceived functioning and well-being in adults, and preliminary evidence for the reliability and construct validity of the SCQoL is provided.

A Possible Index of Fatal Drug Toxicity in Humans

This index (T) has been obtained for 47 drugs commonly encountered in fatalities in England and Wales and it is shown that T is often closely related to the corresponding fatal toxicity in animals, and to physico-chemical factors which are known to be correlated with other measures of human drug toxicity.

Drug policy: striking the right balance.

It is concluded, from a cost-benefit analysis based on pharmacologic, toxicologic, sociologic, and historical facts, that radical steps to repeal the prohibitions on presently illicit drugs would be likely to make matters worse rather than better.

Gamma hydroxy butyrate abuse and dependency

GHB has been increasingly used in rape cases due to its capacity to produce intoxication and amnesia, and the management of patients dependent on GHB is rather complicated due to the high doses of medication that they require to control withdrawal symptoms.

Drug War Heresies: Learning from Other Vices, Times, and Places

  • M. Farrell
  • Political Science
    BMJ : British Medical Journal
  • 2002
Rising levels of serious drug problems put new pressures on old systems that can barely cope anyway, and schools, psychiatric hospitals, and prisons continue to face fresh challenges.

Mortality in relation to smoking: 50 years' observations on male British doctors

A substantial progressive decrease in the mortality rates among non-smokers over the past half century has been wholly outweighed, among cigarette smokers, by a progressive increase in the smoker νNon-smoker death rate ratio due to earlier and more intensive use of cigarettes.