Development of a quantitative real-time PCR assay for detection of unknown alpha-globin gene deletions.

Abstract

BACKGROUND Alpha-Thalassemia is the most common inherited disorder of hemoglobin (Hb) synthesis in the world. Unlike beta-thalassemia, in which non-deletional mutations predominate, most of recognized alpha-thalassemia mutations include deletion of one or both alpha-globin genes. The importance of alpha-thalassemia detection is mainly due to its shared… (More)
DOI: 10.1016/j.bcmd.2010.03.001

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Cite this paper

@article{Fallah2010DevelopmentOA, title={Development of a quantitative real-time PCR assay for detection of unknown alpha-globin gene deletions.}, author={M. Hossein Fallah and Reza Mahdian and Seyyed-Ahmad Aleyasin and Somayeh Jamali and Mina Hayat-Nosaeid and Moretza Karimipour and Marzieh Raeisi and Sirous Zeinali}, journal={Blood cells, molecules & diseases}, year={2010}, volume={45 1}, pages={58-64} }