Development of a psilocin immunoassay for serum and blood samples
@article{Albers2004DevelopmentOA, title={Development of a psilocin immunoassay for serum and blood samples}, author={C. Albers and H. K{\"o}hler and M. Lehr and B. Brinkmann and J. Beike}, journal={International Journal of Legal Medicine}, year={2004}, volume={118}, pages={326-331} }
After the immunisation of rabbits with a psilocin-specific immunogen, polyclonal antisera were obtained. With these antisera a competitive, heterogeneous radioimmunoassay for the detection of psilocin was developed. As tracer a derivative of psilocin was synthesised, which contained a tritiated CH3 group. The antisera showed a specific reaction with psilocin. The cross-reactivity of structurally related endogenous substances like serotonin, tryptophan and tyrosine was below 0.01%. Also common… CONTINUE READING
Figures, Tables, and Topics from this paper
Paper Mentions
11 Citations
Psilocin identified in a DUID investigation.
- Chemistry, Medicine
- Journal of analytical toxicology
- 2006
- 15
- PDF
Immunochemical monitoring of psilocybin and psilocin to identify hallucinogenic mushrooms.
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 2020
Direct Analysis of Psilocin and Muscimol in Urine Samples Using Single Drop Microextraction Technique In-Line with Capillary Electrophoresis
- Chemistry, Medicine
- Molecules
- 2020
- 1
- PDF
Cross-reactivity of the CEDIA buprenorphine assay with opiates: an Austrian phenomenon?
- Chemistry, Medicine
- International Journal of Legal Medicine
- 2005
- 26
A validated method for quantitation of psilocin in plasma by LC–MS/MS and study of stability
- Medicine, Chemistry
- International Journal of Legal Medicine
- 2011
- 15
Biomedical analysis of New Psychoactive Substances (NPS) of natural origin.
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 2019
- 5
References
SHOWING 1-10 OF 22 REFERENCES
The detection of psilocin in human urine.
- Chemistry, Medicine
- Journal of forensic sciences
- 2001
- 52
- Highly Influential
Detection of psilocin in body fluids.
- Chemistry, Medicine
- Forensic science international
- 2000
- 53
- Highly Influential
- PDF
Determination of psilocin and 4-hydroxyindole-3-acetic acid in plasma by HPLC-ECD and pharmacokinetic profiles of oral and intravenous psilocybin in man.
- Chemistry, Medicine
- Pharmaceutica acta Helvetiae
- 1997
- 112
Optimized glucuronide hydrolysis for the detection of psilocin in human urine samples.
- Chemistry, Medicine
- Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
- 2003
- 51
Production and characterization of a monoclonal antibody for sweat-specific protein and its application for sweat identification
- Biology, Medicine
- International Journal of Legal Medicine
- 2002
- 38
Quantitation of psilocin in human plasma by high-performance liquid chromatography and electrochemical detection: comparison of liquid-liquid extraction with automated on-line solid-phase extraction.
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical sciences and applications
- 1998
- 54
- PDF
Synthesis of a psilocin hapten and a protein‐hapten conjugate
- Chemistry, Medicine
- The Journal of pharmacy and pharmacology
- 2002
- 5
The enzymic dephosphorylation and oxidation of psilocybin and psilocin by mammalian tissue homogenates.
- Biology, Medicine
- Biochemical pharmacology
- 1961
- 54
Liquid chromatography-mass spectrometry as a routine method in forensic sciences: a proof of maturity.
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical sciences and applications
- 2000
- 100
- PDF