Development of a preventive vaccine for Ebola virus infection in primates

@article{Sullivan2000DevelopmentOA,
  title={Development of a preventive vaccine for Ebola virus infection in primates},
  author={Nancy J. Sullivan and A. S{\'a}nchez and Pierre E. Rollin and Zhi-Yong Yang and Gary J. Nabel},
  journal={Nature},
  year={2000},
  volume={408},
  pages={605-609}
}
Outbreaks of haemorrhagic fever caused by the Ebola virus are associated with high mortality rates that are a distinguishing feature of this human pathogen. The highest lethality is associated with the Zaire subtype, one of four strains identified to date. Its rapid progression allows little opportunity to develop natural immunity, and there is currently no effective anti-viral therapy. Therefore, vaccination offers a promising intervention to prevent infection and limit spread. Here we… CONTINUE READING

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