Development of a novel therapeutic approach using a retinoic acid-loaded microneedle patch for seborrheic keratosis treatment and safety study in humans.

Abstract

Seborrheic keratosis is one of the most common skin benign tumors in humans with a high occurrence rate of 80%-100% in people > 50 years of age; however, its pathogenesis is still unclear. The standard treatment includes cryotherapy and laser surgery for physically removing lesions. Drug therapy for this condition has not been well established. We aimed to… (More)
DOI: 10.1016/j.jconrel.2013.06.008

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Cite this paper

@article{Hiraishi2013DevelopmentOA, title={Development of a novel therapeutic approach using a retinoic acid-loaded microneedle patch for seborrheic keratosis treatment and safety study in humans.}, author={Yasuhiro Hiraishi and Sachiko Hirobe and Hiroshi Iioka and Ying-shu Quan and Fumio Kamiyama and Hideo Asada and Naoki Okada and Shinsaku Nakagawa}, journal={Journal of controlled release : official journal of the Controlled Release Society}, year={2013}, volume={171 2}, pages={93-103} }