Development of a novel fluorescent probe for nitric oxide detection: 8-(3',4'-diaminophenyl)-difluoroboradiaza-S-indacence.


A novel fluorescent probe, 8-(3',4'-diaminophenyl)-difluoroboradiaza-S-indacence (DABODIPY), was designed and synthesized for monitoring nitric oxide production, which features high photostability and no pH dependency over a wide pH range. The fluorescence of 8-(3',4'-diaminophenyl)-difluoroboradiaza-S-indacence is very low, however, when the probe traps… (More)


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