Development of a novel ex vivo model of corneal fungal adherence

@article{Zhou2010DevelopmentOA,
  title={Development of a novel ex vivo model of corneal fungal adherence},
  author={Qingjun Zhou and Hao Chen and Mingli Qu and Qian Wang and Lingling Yang and Lixin Xie},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2010},
  volume={249},
  pages={693-700}
}
To construct a suitable ex vivo model for the research of molecular mechanisms and the pharmacological screening of fungal adherence on the corneal surface. Mouse eyes were divided into three groups as follows: a control group with normal corneal epithelium, a group with corneal epithelium that was needle-scarified, and a group with corneal epithelium that was completely debrided. All 96 corneas were placed in organ culture and inoculated with 5 μl spore suspensions of Candida albicans at 109… CONTINUE READING

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