Development of a novel continuous culture device for experimental evolution of bacterial populations

@article{Crcy2007DevelopmentOA,
  title={Development of a novel continuous culture device for experimental evolution of bacterial populations},
  author={Eudes de Cr{\'e}cy and David Metzgar and colin. allen and Michel P{\'e}nicaud and Benjamin A. Lyons and Christian J. Hansen and Val{\'e}rie de Cr{\'e}cy-Lagard},
  journal={Applied Microbiology and Biotechnology},
  year={2007},
  volume={77},
  pages={489-496}
}
The availability of a robust and reliable continuous culture apparatus that eliminates wall growth problems would lead to many applications in the microbial field, including allowing genetically engineered strains to recover high fitness, improving biodegradation strains, and predicting likely antibiotic resistance mechanisms. We describe the design and implementation of a novel automated continuous culture machine that can be used both in time-dependent mode (similar to a chemostat) and… CONTINUE READING