Development of a non-infectious rat model of acute exacerbation of idiopathic pulmonary fibrosis.

Abstract

BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease with severe pulmonary fibrosis. The main cause of IPF-associated death is acute exacerbation of IPF (AE-IPF). This study aims to develop a rat model of AE-IPF by two intratracheal perfusions with bleomycin (BLM). METHODS Ninety male Sprague Dawley (SD) rats… (More)
DOI: 10.21037/jtd.2017.01.22

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@article{Chen2017DevelopmentOA, title={Development of a non-infectious rat model of acute exacerbation of idiopathic pulmonary fibrosis.}, author={Shan-Shan Chen and Zhao-fang Yin and Tao Chen and Hui Qiu and Ya-ru Wei and Shan-Shan Du and Yue-ping Jin and Meng-meng Zhao and Qin Wu and Dong Weng and Huiping Li}, journal={Journal of thoracic disease}, year={2017}, volume={9 1}, pages={96-105} }