Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol.

@article{Stoner2002DevelopmentOA,
  title={Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol.},
  author={Gary David Stoner and Bruce Casto and Sherry Ralston and Bill D. Roebuck and Clifford B Pereira and George S. Bailey},
  journal={Carcinogenesis},
  year={2002},
  volume={23 2},
  pages={265-72}
}
Indole-3-carbinol (I-3-C) is among the most widely and popularly known antiestrogens. Due to its putative chemopreventive action, I-3-C is being marketed to the general public in health food establishments. Although it has been demonstrated to prevent cancer in animal bioassays, I-3-C also acts as a promoter in the liver and colon. Because of this potential dual biological activity, it is important to investigate both the inhibitory and promotional activities of I-3-C in multi-organ… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Similar Papers

Loading similar papers…