Development of a molecular biomarker for detecting intersex after exposure of male medaka fish to synthetic estrogen.

@article{Zhao2012DevelopmentOA,
  title={Development of a molecular biomarker for detecting intersex after exposure of male medaka fish to synthetic estrogen.},
  author={Yanbin Zhao and Jianying Hu},
  journal={Environmental toxicology and chemistry},
  year={2012},
  volume={31 8},
  pages={
          1765-73
        }
}
Although intersex of fish species has been widely reported in aquatic environments, there is no appropriate biomarker of the effects to assess the occurrence of intersex. In the present study, mRNA expression profiles of 14 genes, which are either involved in ovary development and maintenance or have relatively high mRNA transcription levels in ovarian gene expression profiles in fish species, were comprehensively evaluated in male Japanese medaka (Oryzias latipes) exposed to 17… CONTINUE READING
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