Development of a model of natural infection with Mycobacterium bovis in white-tailed deer.

  title={Development of a model of natural infection with Mycobacterium bovis in white-tailed deer.},
  author={Mitchell V Palmer and Diana L Whipple and Steven C. Olsen},
  journal={Journal of wildlife diseases},
  volume={35 3},
The objective of this study was to develop a suitable experimental model of natural Mycobacterium bovis infection in white-tailed deer (Odocoileus virginianus), describe the distribution and character of tuberculous lesions, and to examine possible routes of disease transmission. In October 1997, 10 mature female white-tailed deer were inoculated by intratonsilar instillation of 2 x 10(3) (low dose) or 2 x 10(5) (high dose) colony forming units (CFU) of M. bovis. In January 1998, deer were… CONTINUE READING


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