Development of a mature fungal technology and production platform for industrial enzymes based on a Myceliophthora thermophila isolate, previously known as Chrysosporium lucknowense C1

@inproceedings{Visser2011DevelopmentOA,
  title={Development of a mature fungal technology and production platform for industrial enzymes based on a Myceliophthora thermophila isolate, previously known as Chrysosporium lucknowense C1},
  author={Hans Visser and Vivi Joosten and Peter J. Punt and Alexander V Gusakov and Phil T. Olson and Rob Joosten and Jeffrey R. Bartels and J. Ir Visser and Arkady P. Sinitsyn and Mark Aaron Emalfarb and Jan C. Verdoes and Jan Wery},
  year={2011}
}

• Hans Visser, Vivi Joosten, +9 authors Jan Wery
• Published 2011
• DOI:10.1089/ind.2011.7.214

The filamentous fungus C1 was developed into an expression platform for screening and production of diverse industrial enzymes. C1 shows a lowviscosity morphology in submerged culture, enabling the use of complex growth and production media. This morphology furthermore allowed C1 to be used as a host for high-throughput robotic screening of gene libraries. A C1-genetic toolbox was developed, which enabled the generation of a large collection of dedicated C1 host strains and gene-expression… CONTINUE READING

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