Development of a magnetic particle immunoassay for polybrominated diphenyl ethers and application to environmental and food matrices.

@article{Shelver2008DevelopmentOA,
  title={Development of a magnetic particle immunoassay for polybrominated diphenyl ethers and application to environmental and food matrices.},
  author={Weilin L Shelver and Carmen D Parrotta and Richard A. Slawecki and Qing X Li and Michael George Ikonomou and Dami{\'a} Barcel{\'o} and S{\'i}lvia Lacorte and Fernando L{\'o}pez Rubio},
  journal={Chemosphere},
  year={2008},
  volume={73 1 Suppl},
  pages={S18-23}
}
A sensitive magnetic particle enzyme-linked immunoassay (ELISA) was developed to analyze polybrominated diphenyl ethers (PBDEs) in water, milk, fish, and soil samples. The assay was rapid and can be used to analyze fifty samples in about 1h after sample cleanup. The assay has a limit of detection (LOD) below 0.1 ppb towards the following brominated diphenyl ether (BDE) congeners: BDE-47, BDE-99, BDE-28, BDE-100, and BDE-153, with the LOD approximately the same as GC-NCI-MS. The congeners most… CONTINUE READING

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