Development of a low-cost sterilization biological indicator using Bacillus atrophaeus by solid-state fermentation

@article{Sella2011DevelopmentOA,
  title={Development of a low-cost sterilization biological indicator using Bacillus atrophaeus by solid-state fermentation},
  author={Sandra Regina Barroso Ruiz Sella and Belquis Pal{\'a}cio Guizelini and Pedro H. Zanello and Luciana P S Vandenberghe and Ciro Alberto de Oliveira Ribeiro and Jo{\~a}o Carlos Minozzo and Carlos Ricardo Soccol},
  journal={Applied Microbiology and Biotechnology},
  year={2011},
  volume={93},
  pages={151-158}
}
The production of biological indicators involving bacterial sporulation and multi-step downstream processes has been described. The goal of the present work was to use fermented material as the final product in a biological indicator, thereby reducing processing steps and costs. The performance of three different inexpensive supports (vermiculite, sand, and sugarcane bagasse) was assessed by determining Bacillus atrophaeus sporulation during solid-state fermentation and by assessing the direct… CONTINUE READING
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