Development of a live tissue microtome: reflections of an amateur machinist

@article{Krumdieck2013DevelopmentOA,
  title={Development of a live tissue microtome: reflections of an amateur machinist},
  author={Carlos L. Krumdieck},
  journal={Xenobiotica},
  year={2013},
  volume={43},
  pages={2 - 7}
}
Live circular tissue slices of nearly identical diameter and thickness can be generated from most tissues by the use of two instruments; a coring tool to cut cylindrical tissue cores which are subsequently sliced by a microtome into thin circular sections 5–8 mm in diameter and 50–300 microns thick. The sections are of very similar geometry permitting direct comparisons without normalization. Both instruments operate submerged in a cold isotonic medium that caries the cut slices outside the… 
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