Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption.

@article{Lang2010DevelopmentOA,
  title={Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption.},
  author={Roman Lang and Anika Wahl and Thomas Skurk and Erkan Firat Yagar and Ludger Schmiech and Rudolf Eggers and Hans Hauner and Thomas Hofmann},
  journal={Analytical chemistry},
  year={2010},
  volume={82 4},
  pages={1486-97}
}
The paper reports on the development of an accurate hydrophilic liquid interaction chromatography tandem mass spectrometry (HILIC-MS/MS) based stable isotope dilution analysis for the simultaneous quantitation of the food-derived bioactive pyridines trigonelline, nicotinic acid, nicotinamide, and N-methylpyridinium, as well as their key metabolites nicotinamide-N-oxide, N-methylnicotinamide, N-methyl-2-pyridone-5-carboxamide, N-methyl-4-pyridone-5-carboxamide, and N-methyl-2-pyridone-5… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Identification of coffee components that stimulate dopamine release from pheochromocytoma cells (PC-12).

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2012
View 3 Excerpts

Similar Papers

Loading similar papers…