Development of a high-performance liquid chromatography method based on a core-shell column approach for the rapid determination of multiclass polyphenols in grape pomaces.

@article{Fontana2016DevelopmentOA,
  title={Development of a high-performance liquid chromatography method based on a core-shell column approach for the rapid determination of multiclass polyphenols in grape pomaces.},
  author={Ariel Ram{\'o}n Fontana and Andrea Antoniolli and Rub{\'e}n A Bottini},
  journal={Food chemistry},
  year={2016},
  volume={192},
  pages={1-8}
}
A rapid and economically affordable reverse-phase chromatographic approach based on a core-shell column with high-performance liquid chromatography multi-wavelength detector (HPLC-MWD) is proposed for the quantification and quality control of multiclass polyphenols (PPs). The separation of 20 relevant polyphenols from grape pomace extracts (GPEs) was achieved in less than 12 min by using a Kinetex C18 column (3.0 mm × 100 mm, 2.6 μm) with a gradient system of ultrapure water (0.1% formic acid… CONTINUE READING