Development of a genotyping microarray for studying the role of gene-environment interactions in risk for lung cancer.

@article{Baldwin2013DevelopmentOA,
  title={Development of a genotyping microarray for studying the role of gene-environment interactions in risk for lung cancer.},
  author={Don A Baldwin and Chris P. Sarnowski and Sabrina A Reddy and Ian A. Blair and Margie L. Clapper and Philip Lazarus and Mingyao Li and Joshua E. Muscat and Trevor M. Penning and Anil Vachani and Alexander S. Whitehead},
  journal={Journal of biomolecular techniques : JBT},
  year={2013},
  volume={24 4},
  pages={
          198-217
        }
}
A microarray (LungCaGxE), based on Illumina BeadChip technology, was developed for high-resolution genotyping of genes that are candidates for involvement in environmentally driven aspects of lung cancer oncogenesis and/or tumor growth. The iterative array design process illustrates techniques for managing large panels of candidate genes and optimizing marker selection, aided by a new bioinformatics pipeline component, Tagger Batch Assistant. The LungCaGxE platform targets 298 genes and the… 

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