Development of a genetically encodable FRET system using fluorescent RNA aptamers

@inproceedings{Jepsen2017DevelopmentOA,
  title={Development of a genetically encodable FRET system using fluorescent RNA aptamers},
  author={Mette D E Jepsen and Steffen M Sparvath and Thorbj\orn B Nielsen and Ane H Langvad and Guido Grossi and Kurt Vesterager Gothelf and Ebbe Sloth Andersen},
  booktitle={Nature Communications},
  year={2017}
}
Fluorescent RNA aptamers are useful as markers for tracking RNA molecules inside cells and for creating biosensor devices. Förster resonance energy transfer (FRET) based on fluorescent proteins has been used to detect conformational changes, however, such FRET devices have not yet been produced using fluorescent RNA aptamers. Here we develop an RNA aptamer… CONTINUE READING