Development of a fluorimetric detection method for cinnabarinic acid using ortho-tolyl hydrazine as the derivatization reagent.

Abstract

A fluorimetric detection method for one of the tryptophan metabolites, cinnabarinic acid (CA), which has recently been reported to have the ability to induce apoptosis in thymocytes, was developed using o-tolyl hydrazine (TH) as the derivatization reagent. The carbonyl group at position 3 in CA was tagged with the hydrazino moiety of TH at 100 degrees C for… (More)
DOI: 10.1002/bmc.1281

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