Development of a diagnostic microarray assay to assess the risk of recurrence of prostate cancer based on PITX2 DNA methylation.

@article{Schatz2010DevelopmentOA,
  title={Development of a diagnostic microarray assay to assess the risk of recurrence of prostate cancer based on PITX2 DNA methylation.},
  author={Philipp Schatz and Dimo Dietrich and Thomas K{\"o}nig and M. Burger and Antje Lukas and Ina Fuhrmann and Glen Kristiansen and Robert Franz St{\"o}hr and Matthias Schuster and Ralf Lesche and Gunter Weiss and John M. Corman and Arndt Hartmann},
  journal={The Journal of molecular diagnostics : JMD},
  year={2010},
  volume={12 3},
  pages={345-53}
}
Prostate cancer is among the most common cancers. Although it has a relatively good prognosis, 15 to 30% of men with prostate cancer experience a relapse after radical prostatectomy. Identifying patients with an aggressive tumor will therefore help to improve prostate cancer management. DNA methylation of PITX2 has been established in several studies as a prognostic biomarker for breast and prostate cancer. These case control studies were conducted using research assay components; to facilitate… CONTINUE READING

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