Development of a competitive index assay to evaluate the virulence of Listeria monocytogenes actA mutants during primary and secondary infection of mice.

@article{Auerbuch2001DevelopmentOA,
  title={Development of a competitive index assay to evaluate the virulence of Listeria monocytogenes actA mutants during primary and secondary infection of mice.},
  author={Victoria Auerbuch and Laurel L Lenz and Daniel A Portnoy},
  journal={Infection and immunity},
  year={2001},
  volume={69 9},
  pages={5953-7}
}
We developed a competitive index assay for murine listeriosis that tests the virulence of Listeria monocytogenes strains in different organs and at various times postinoculation. Studies presented here demonstrate the reproducibility of this assay during primary and secondary infection of inbred and outbred mice. We verified the validity of this assay by performing competitive index analysis of a well-characterized strain of L. monocytogenes lacking the actA gene. In addition, we found that… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
36 Citations
27 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Similar Papers

Loading similar papers…