Development of a chitosan-based nanoparticle formulation for ophthalmic delivery of honokiol.


In this study, honokiol-loaded chitosan/sulfobutylether-β-cyclodextrin nanoparticles (HK-CS-NPs) were prepared for ophthalmic drug delivery systems. An inclusion complex of honokiol and sulfobutylether-β-cyclodextrin was used to generate large amounts of insoluble honokiol to be incorporated into chitosan nanoparticles, which were prepared through… (More)
DOI: 10.2174/1567201814666170419113933