Development of a Staphylococcus aureus vaccine against mastitis in dairy cows. I. Challenge trials.

@article{Leitner2003DevelopmentOA,
  title={Development of a Staphylococcus aureus vaccine against mastitis in dairy cows. I. Challenge trials.},
  author={Gabriel Leitner and Evgenia Lubashevsky and Anita Glickman and Marta Winkler and Arthur Saran and Zeev Trainin},
  journal={Veterinary immunology and immunopathology},
  year={2003},
  volume={93 1-2},
  pages={
          31-8
        }
}
A vaccine composed of three field isolates of Staphylococcus aureus (S. aureus) derived from cases of mastitis in cows was developed. The vaccine was administered to nine uninfected cows while 10 other cows were used as controls. All cows were challenged with a highly virulent S. aureus strain administered into two quarters of each cow. Quarters were tested for clinical signs, secretion of S. aureus, and somatic cell count (SCC). No systemic effects were observed in any of the cows, vaccinated… CONTINUE READING

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