Development of a Sendai virus vector-based AIDS vaccine inducing T cell responses

  title={Development of a Sendai virus vector-based AIDS vaccine inducing T cell responses},
  author={Sayuri Seki and Tetsuro Matano},
  journal={Expert Review of Vaccines},
  pages={119 - 127}
Virus-specific CD8+ T-cell responses play a major role in the control of HIV replication, and induction of HIV-specific T-cell responses is an important strategy for AIDS vaccine development. Optimization of the delivery system and immunogen would be the key for the development of an effective T cell-based AIDS vaccine. Heterologous prime-boost vaccine regimens using multiple viral vectors are a promising protocol for efficient induction of HIV-specific T-cell responses, and the development of… 
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