Development of a Protein Biomarker Panel to Detect Non-Small-Cell Lung Cancer in Korea.

@article{Jung2017DevelopmentOA,
  title={Development of a Protein Biomarker Panel to Detect Non-Small-Cell Lung Cancer in Korea.},
  author={Young Ju Jung and Evaldas Katilius and Rachel M. Ostroff and Youndong Kim and Minkyoung Seok and Sujin Lee and Seongsoo Jang and Woo Sung Kim and Chang Min Choi},
  journal={Clinical lung cancer},
  year={2017},
  volume={18 2},
  pages={e99-e107}
}
BACKGROUND Lung cancer screening using low-dose computed tomography reduces lung cancer mortality. However, the high false-positive rate, cost, and potential harms highlight the need for complementary biomarkers. We compared the diagnostic performance of modified aptamer-based protein biomarkers with Cyfra 21-1. PATIENTS AND METHODS Participants included 100 patients diagnosed with lung cancer, and 100 control subjects from Asan Medical Center (Seoul, Korea). We investigated candidate… CONTINUE READING

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