Development of a DIVA (Differentiating Infected from Vaccinated Animals) strategy using a vaccine containing a heterologous neuraminidase for the control of avian influenza

@article{Capua2003DevelopmentOA,
  title={Development of a DIVA (Differentiating Infected from Vaccinated Animals) strategy using a vaccine containing a heterologous neuraminidase for the control of avian influenza},
  author={I. Capua and C. Terregino and G. Cattoli and F. Mutinelli and J. F. Rodr{\'i}guez},
  journal={Avian Pathology},
  year={2003},
  volume={32},
  pages={47 - 55}
}
  • I. Capua, C. Terregino, +2 authors J. F. Rodríguez
  • Published 2003
  • Biology, Medicine
  • Avian Pathology
  • The present paper reports of the development and validation of a control strategy for avian influenza infections in poultry. The "DIVA" (Differentiating Infected from Vaccinated Animals) strategy is based on the use of an inactivated oil emulsion vaccine containing the same haemagglutinin (H) subtype as the challenge virus, but a different neuraminidase (N). The possibility of using the heterologous N subtype, to differentiate between vaccinated and naturally infected birds, was investigated… CONTINUE READING

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