Development of a Cost-Effective and Simple Protocol for Decellularization and Preservation of Human Amniotic Membrane as a Soft Tissue Replacement and Delivery System for Bone Marrow Stromal Cells.

@article{Gholipourmalekabadi2015DevelopmentOA,
  title={Development of a Cost-Effective and Simple Protocol for Decellularization and Preservation of Human Amniotic Membrane as a Soft Tissue Replacement and Delivery System for Bone Marrow Stromal Cells.},
  author={Mazaher Gholipourmalekabadi and Masoud Mozafari and Mohammad Salehi and Amelia Seifalian and Mojgan Bandehpour and Hossein Ghanbarian and Aleksandra Malgorzata Urbanska and Marzieh Sameni and Ali Samadikuchaksaraei and Alexander M. Seifalian},
  journal={Advanced healthcare materials},
  year={2015},
  volume={4 6},
  pages={918-26}
}
The aim of this study is to develop a simple and cost-effective method for decellularization and preservation of human amniotic membrane (HAM) as a soft tissue replacement and a delivery system for stem cells. The HAM is decellularized (D) using new chemical and mechanical techniques. The decellularization scaffold is evaluated histologically and fully characterized. The cell adhesion and proliferation on the scaffold are also investigated and the biocompatibility of D tissues is evaluated in… CONTINUE READING
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