Development of a Composite Primary Outcome Score for Children with Attention-Deficit/Hyperactivity Disorder and Emotional Dysregulation.

@article{Johnstone2020DevelopmentOA,
  title={Development of a Composite Primary Outcome Score for Children with Attention-Deficit/Hyperactivity Disorder and Emotional Dysregulation.},
  author={J. Johnstone and Brenda M Y Leung and P. Srikanth and I. Hatsu and L. Perez and B. Gracious and Gabriella Tost and M. Aman and K. Gadow and R. Findling and O. Bukstein and L. E. Arnold},
  journal={Journal of child and adolescent psychopharmacology},
  year={2020}
}
  • J. Johnstone, Brenda M Y Leung, +9 authors L. E. Arnold
  • Published 2020
  • Medicine
  • Journal of child and adolescent psychopharmacology
  • Objective: Study goals were to (1) provide a rationale for developing a composite primary outcome score that includes symptom severity for attention-deficit/hyperactivity disorder (ADHD) and emotional dysregulation, plus symptom-induced impairment; (2) demonstrate weighting methods to calculate the composite score using a sample of children diagnosed with ADHD and aggression; and (3) identify the optimal weighting method most sensitive to change, as measured by effect sizes. Methods: We… CONTINUE READING
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