Corpus ID: 7746514

Development of a Combined Bovine Colostrum and Immune-Stimulatory Carbohydrate Nutraceutical for Enhancement of Endogenous Stem Cell Activity

@article{Webster2013DevelopmentOA,
  title={Development of a Combined Bovine Colostrum and Immune-Stimulatory Carbohydrate Nutraceutical for Enhancement of Endogenous Stem Cell Activity},
  author={Gill A. Webster and Peter Lehrke},
  journal={The Open Nutraceuticals Journal},
  year={2013},
  volume={6}
}
There is increasing interest in the use of functional foods to activate natural stem cell associated repair path- ways resulting in improved health and well-being. Bovine Alpha Lipid colostrum, a proprietary formulation, induced stem cell associated cytokines and growth factor, GCSF, IL-6 and VEGF and also enhanced the differentiation of bone marrow stem cells in vitro. To boost colostrum activity, commercially available natural extracts of immune stimulatory carbohy- drates were screened for… Expand

Tables from this paper

The Nutraceutical Alpha Lipid ColostemTM Modulates Peripheral Bloodand Bone Marrow Stem Cell Subsets following Oral Supplementation
TLDR
Findings further strengthen the hypothesis that dietary supplementation with a synergistic combination of bovine colostrum and immune stimulatory carbohydrates promotes coherent activation of the stem cell niche. Expand
Dietary lyophilized colostrum alters distribution of goblet cells and the intestinal epithelium of Piaractus mesopotamicus
TLDR
The presence of unidentified substances from the bovine colostrum determined a reaction in intestinal epithelium with subsequent increased production of mucin, which contributes to a better understanding of basic histology of neotropical fish species, that still demands for basic studies about enteric physiology. Expand
Potential Effect of Bovine Colostrum on Tongue Mucosa in Ovariectomized Rats
Background: Menopause is a physiologic stage in women life. Oral cavity is subjective to the endocrine disturbance linked with menopause particularly in sex steroid hormone deficiency. Aim of study:Expand

References

SHOWING 1-10 OF 65 REFERENCES
Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects
TLDR
Stem-Kine supplementation may be useful as a stimulator of reparative processes associated with mobilization of hematopoietic and endothelial progenitors as detected by KDR-1/CD34 staining and colony forming assays. Expand
Oral administration of insulin receptor-interacting lectins leads to an enhancement in the hematopoietic stem and progenitor cell pool of mice.
TLDR
The data suggest that these lectins may serve as micronutrients for therapeutic purposes in hematological deficiencies by protecting the stem cell pool of mice by activating ERK signaling and reducing the oxidative stress in the niche. Expand
Spirulina Promotes Stem Cell Genesis and Protects against LPS Induced Declines in Neural Stem Cell Proliferation
TLDR
The hypothesis that a diet enriched with spirulina and other nutraceuticals may help protect the stem/progenitor cells from insults is supported. Expand
Immune components of bovine colostrum and milk.
TLDR
An overview is presented of the immune factors in colostrum and milk as well as the results of research aimed at realizing this untapped value in milk. Expand
The safety of New Zealand bovine colostrum: nutritional and physiological evaluation in rats.
TLDR
It can be concluded that the young growing rats had no observed toxicological and histopathological abnormalities caused by colostrum at the levels of supplementation used. Expand
Bovine colostrum supplementation attenuates the decrease of salivary lysozyme and enhances the recovery of neutrophil function after prolonged exercise.
TLDR
4 weeks of bovine COL supplementation limits the immunodepressive effects induced by an acute prolonged physical stressor, such as exercise, which may confer some benefits to host defence. Expand
Immunostimulatory activities of polysaccharide extract isolated from Curcuma longa.
  • G. Yue, B. Chan, +6 authors C. Lau
  • Chemistry, Medicine
  • International journal of biological macromolecules
  • 2010
TLDR
The results showed that the high polarity fraction of the hot water extract exhibited stimulatory effects on PBMC proliferation as shown in [methyl-(3)H]-thymidine incorporation assay, revealing the potential use of C. longa crude extract as an adjuvant supplement for cancer patients, whose immune activities were suppressed during chemotherapies. Expand
Prophylactic application of bovine colostrum ameliorates murine colitis via induction of immunoregulatory cells.
TLDR
Prophylactic administration of colostrum improved clinical symptoms of colorectal inflammation in a well-established mouse model of DSS-induced colitis and the underlying immunomodulatory mechanisms were targeted. Expand
Peptide therapy and the gastroenterologist: colostrum and milk-derived growth factors
TLDR
The relative merits of using colostral fractions as opposed to an individual recombinant peptide for the treatment of these various conditions are discussed. Expand
Isolation of two new proteins from bovine colostrum which stimulate epidermal growth factor-dependent colony formation of NRK-49F cells.
TLDR
The results suggest that BC-1 and BC-2 belong to a new class of mitogen/inhibitors, though their biological activities resemble those of TGF-beta. Expand
...
1
2
3
4
5
...