Development of a Bacterial Biosensor for Rapid Screening of Yeast p-Coumaric Acid Production.

@article{Siedler2017DevelopmentOA,
  title={Development of a Bacterial Biosensor for Rapid Screening of Yeast p-Coumaric Acid Production.},
  author={Solvej Siedler and Narendar K Khatri and Andrea Zsoh{\'a}r and Inge Kj{\ae}rb\olling and Michael Vogt and Petter Hammar and Christian Friberg Nielsen and Jan Marienhagen and Morten Otto Alexander Sommer and Haakan N. Joensson},
  journal={ACS synthetic biology},
  year={2017},
  volume={6 10},
  pages={1860-1869}
}
Transcription factor-based biosensors are used to identify producer strains, a critical bottleneck in cell factory engineering. Here, we address two challenges with this methodology: transplantation of heterologous transcriptional regulators into new hosts to generate functional biosensors and biosensing of the extracellular product concentration that… CONTINUE READING