Development of Tobacco necrosis virus A as a vector for efficient and stable expression of FMDV VP1 peptides.

@article{Zhang2010DevelopmentOT,
  title={Development of Tobacco necrosis virus A as a vector for efficient and stable expression of FMDV VP1 peptides.},
  author={Yongliang Zhang and Jiang Li and Heng Pu and Jin Jin and Xiaofeng Zhang and Mingkuan Chen and Bin Wang and Chenggui Han and Jialin Yu and Dawei Li},
  journal={Plant biotechnology journal},
  year={2010},
  volume={8 4},
  pages={506-23}
}
Plant virus-based expression systems provide attractive alternatives for production of animal virus-originated antigenic peptides. In the present study, an infectious cDNA clone of Tobacco necrosis virus A Chinese isolate (TNV-A(C)) was used for expression of different peptides derived from Foot and mouth disease virus (FMDV) serotype O VP1 fused downstream of the coat protein (CP) open reading frame (ORF). Chenopodium amaranticolor inoculated with in vitro transcripts of the chimaeras… CONTINUE READING

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