Development of Thy-1 antigen on cerebellar neurons in culture.

The Thy-1.1 cell surface antigen was demonstrated by indirect immunofluorescence on two types of neurons in dissociated cell cultures of developing rat cerebellum. In cultures from postnatal rats, small cells predominated. They bound tetanus toxin, a neuronal marker, and did not have the capacity to take up gamma-aminobutyric acid (GABA) as measured by… CONTINUE READING