Development of T7 phage and T7 phage containing apurinic sites in an exonuclease III, endonuclease IV double mutant of Escherichia coli.

Abstract

The development of bacteriophage T7 was examined in an Escherichia coli double mutant defective for the two major apurinic, apyrimidinic endonucleases (exonuclease III and endonuclease IV, xth nfo). In cells infected with phages containing apurinic sites, the defect in repair enzymes led to a decrease of phage survival and a total absence of bacterial DNA… (More)

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@article{Snchez1992DevelopmentOT, title={Development of T7 phage and T7 phage containing apurinic sites in an exonuclease III, endonuclease IV double mutant of Escherichia coli.}, author={Giselle S{\'a}nchez and Margaret D Mamet-Bratley}, journal={Biochemistry and cell biology = Biochimie et biologie cellulaire}, year={1992}, volume={70 7}, pages={605-8} }